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Resilience: why some people get through crises without falling ill

A DW documentary visits labs in Germany and psychiatrist Boris Cyrulnik to show what genes, hormones and environment reveal about withstanding stress.

· 2 min read · Sources

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DW Documental · “Salud mental y resiliencia - los secretos del alma | DW Documental”

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In 1 minute

  • Researchers in Mainz, Munich and Freiburg study why the same burden of stress makes some people ill and spares others.
  • The findings involve how we appraise stress, the FKBP5 gene, cortisol regulation and epigenetic marks that psychotherapy appears to change.
  • Much of the evidence still comes from mice and small samples; the film treats resilience as a process, not a gift.
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Full article

In the early hours of a night in 2019, two 16-year-old friends, Luca and Freddy, left a party, got caught up in a trivial fight and were dragged under a train. Georg, Luca's father, and Celine, Freddy's mother, went through the worst a family can face. What kept them standing is the question that drives this documentary: why does the same burden of stress break some people and spare others?

Salud mental y resiliencia is a German production by Deutsche Welle, in the Spanish-language version made by the broadcaster itself. Between the stories of the two families, the film visits laboratories in Germany and the French psychiatrist Boris Cyrulnik.

What the labs found

In Mainz, home to what the film calls Europe's largest resilience research center, neuroscientist Raffael Kalisch has followed about 200 young people in the transition to adulthood since 2016. Every three months they answer questionnaires, undergo brain scans and hand over strands of hair, in which researchers measure the cortisol accumulated over the previous months. A pattern emerges: those who appraise their own stress more positively tend to be better protected. At the same institute, experiments with mice suggest that resilience is not ignoring danger but telling threat apart from safety.

In Munich, at the Max Planck Institute of Psychiatry, Elisabeth Binder studies the FKBP5 gene. Certain variants disrupt the signal that tells the brain there is already enough cortisol, so the stress response is slow to switch off. In Freiburg, psychiatrist Katharina Domschke shows that life events alter chemical marks on another gene, MAOA, and that patients with a fear of heights treated with exposure therapy saw those marks return to the levels of healthy people.

Childhood, control and politics

Cyrulnik, who lost his parents in the Holocaust and popularized the term resilience, insists on the earliest years of life and on the role of the state: his work inspired France's program for a child's first thousand days. In Mainz, psychologist Michèle Wessa studies learned helplessness and takes into schools a self-efficacy training that begins by remembering what went right.

Caveats

Many of the results come from mice, simple cell models or small groups, as the film acknowledges in the Freiburg case. A drug targeting FKBP5 is still only a project. And Wessa warns against turning resilience into a demand for productivity.

Why watch

Because it brings together the laboratory and real grief without forcing a happy ending. Georg and Celine set up a violence prevention foundation to give their loss some meaning, and the film closes on the idea that resilience is not a permanent state but a process that never reaches 100 percent.

Sources and references for this article

Salud mental y resiliencia - los secretos del alma | DW Documental. DW Documental, YouTube, 20 Jan 2024Leibniz Institute for Resilience Research (LIR), official siteBoris Cyrulnik, Wikipedia (in Portuguese)Elisabeth Binder, Wikipedia

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